Pharmaceutical product development suppository hardness testing
Laboratory Practice 1: Suppositories
The effect of different PEG dosages on the physical properties of suppositories. The suppository mold was calibrated with PEG before preparation. To determine the effect of different components of PEG matrix on the physical properties of suppositories.
Suppositories are solid dosage forms of various sizes, appearances (shapes), and weights designed to be administered by the rectal route, where they melt, soften, or dissolve to do their job. They can be easily inserted into a predetermined orifice without causing excessive expansion.
Equipment and materials
Model: One automatic suppository hardness tester (ST-Z16)
1. Select 10 suppositories and use Shengtai Instrument automatic Suppository hardness tester (ST-Z16) to test the uniformity of diameter, thickness and hardness.
In this experiment, 10 groups of suppositories were selected to measure their thickness, diameter and hardness. According to the results obtained, the suppository thickness, suppository diameter. Hardness results for suppositories ranged from 1789.100 to 1887.400. The uniformity of the suppository can be demonstrated by calculating the deviation.
Shengtai instrument automatic suppository hardness tester (ST-Z16) is an ideal instrument for measuring suppository hardness. Suppository hardness is important to ensure variation in hardness. If there is a significant deviation from the required normal range, the manufacturer cannot continue to manufacture the drug. If the suppository passes the hardness test, it is a good suppository.
They have uniform diameter, thickness and hardness by suppository hardness test. It is measured by shengtai Instrument automatic suppository hardness tester (ST-Z16).