Principle of method for determination of the freezing point of dibutyl hydroxyl toluene
Medicinal adjuvant dibutyl hydroxyl toluene as antioxidant
Chinese name dibutyl hydroxyl toluene
Chinese pinyin Erdingjiqiangjijiabe
English name Butylated Hydroxytoluene
Molecular formula and molecular weight C15H24O 220.35
CAS number [128-37-0]
Source (name), content (potency)
This product is 2, 6-di-tert-butyl (1, 1-dimethylethyl) -4-methyl phenol.
Including C15H24O should be 95.0% ~ 105.0%.
Properties The product is colorless, white or almost white crystalline or crystalline powder.
This product is soluble in ethanol, insoluble in water and propylene glycol.
Condensation point The condensation point of this product is determined by 2020 Pharmacopoeia General Rule 0613.
Principle: Determine the high temperature at which a drug remains unchanged for a short period of time when condensed from a liquid to a solid.
Some drugs have certain solidification point, purity change, the solidification point will also change.
Determining the condensation point can distinguish or check the purity of the drug.
ST203B automatic drug freezing point meter (developed and produced by Shandong Shengtai Instrument Co., Ltd.) is designed and manufactured according to the general rule 0613 freezing point determination method of Chinese Pharmacopoeia in 2020. It is also in line with the freezing point determination method of USP40 (United States Pharmacopoeia 40 version) USP40 651 in a certain temperature range.